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Hepatocytes available

Cryo-plateable Rat SD pooled Hepatocytes are available ! More...

ISSX Workshop - October 2016

ISSX Workshop in Boston on 27-28th October 2016 More...

CAAT ACADEMY - 2017

CAAT ACADEMY 2017 PROGRAM More...
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Latest publications

  • Stable overexpression of the constitutive androstane receptor reduces the requirement for culture with dimethyl sulfoxide for high drug metabolism in HepaRG cells.Van der Mark VA, de Waart DR, Shevchenko V, Oude Elferink RP
    Drug Metab Dispos, Oct 2016
  • Early Alterations of Bile Canaliculi Dynamics and the Rho Kinase/Myosin Light Chain Kinase Pathway Are Characteristics of Drug-Induced Intrahepatic Cholestasis.van Wenum M, Adam AA, Hakvoort TB, Shevchenko V, van Gulik TM, Chamuleau RA, Hoekstra R
    Drug Metab Dispos, Aug 2016
  • Direct and quantitative evaluation of the human CYP3A4 contribution (fm) to drug clearance using the in vitro SILENSOMES model.Parmentier Y, Pothier C, Delmas A, Caradec F,Trancart MM,Guillet F,Bouaita B,Chesne C,Brian Houston J,Walther B.
    Xenobiotica, Aug 2016
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