News

14th ISSX Meeting 26th & 29th June - Meet our Team !

ISSX 2017

The 14th European ISSX Meeting will take place at the Guerzenich Hall in Cologne (Germany) on the 26th to the 29th of June 2017. Our Team will be there to represent Biopredic International. This meeting will bring together individuals who are actively working on drug/xenobiotic research in diverse fields including basic and clinical pharmacology and therapeutics, toxicology, oncology, endocrinology, physiology, biochemistry, medicinal chemistry, molecular and strucutral biology, and genetics.

 

Meet our Team at the ISSX Cologne

Biopredic International will be reprensented by : 

  • Christophe Chesné, PharmD & PhD, our Chief Executive Officer
  • Solenne Martin, PhD, Project Manager & Study Director
  • Ashwani Sharma, PhD, In Silico Project Manager & Customer Relationship Manager

Right now, you can schedule an appointment with our team during this special event.

 

Poster & Symposium

We are proud to present you our new poster at the ISSX Cologne, during the Session 2 on Wednesday 28th of June:

P95 "Use of SilensomesTM for the analysis of the inhibitory effect of Amiodarone on Warfarin metabolism". Claudia FracassoIRCCSLavinia CantoniIRCCSALice PassoniIRCCSRenzo BagnatiIRCCSMarco GobbiIRCCS;Ashwani SharmaBIOPREDIC INTERNATIONALChristophe ChesneBIOPREDIC INTERNATIONAL


On Wednesday 28th of June, you could also follow our presentation during the Lonza Industry-Sponsored Symposium (Industry-Sponsored Symposia (ISS) are commercially-supported educational sessions held in conjunction with the 14th European ISSX Meeting):

Direct and quantitative evaluation of CYP450 contribution (fm) to drug clearance using the in vitro model Silensomes™ by Ashwani Sharma


 ♦ Tuesday, June 13 2017
http://www.biopredic.com/rubrique-news?cun=pub_aff_breve_partage.208&action=p 
  

CAAT ACADEMY 23-23 June 2017 - BIOPREDIC INTERNATIONAL SESSION

 
 
caat academy 2017
 
For the second time, Biopredic International is proudly contributing to the CAAT ACADEMY 2017 program
 

Biopredic International will host a special training session about hepatotoxicity: "Update on the hepatotoxicity AOP landscape and on the ADMET field [SEASON 2]"

Abstract : 
The relevant systems and biomarkers for adressing hepatotoxicity and DDI issues will be the focus for this training. Prediction of hepatotoxicity remains a challenge nowadays. The session will cover those new systems that are commercially available together with their relevance for predicting issues related to Cholestasis, genotoxicity. Participants will be trained on 3 models with various cell systems and Silensomes (fm (fractions metabolized) evaluation).

Full program:

Thursday, June 22nd 2017


Lectures

Development and validation of an AOP from bile salt export pump inhibition to cholestasis.
With Mathieu Vinken, Vrije universiteit Brussel - Belgium


HepaRG™ hep+ and biological tracers for a new in vitro micronucleus assay.

With Gladys Mirey , INRA - France

 

HepatoPearl 3D cellular model and their application in High throughput DDI screening.

With Noushin Dianat, CYPRIO - France


HepaRG™ Knock out cell models for ADME/Tox Applications.

With David Thompson, MilliporeSigma - USA


An integrated in vitro - in silico system to predict liver toxicity of compounds.

With Dr Kas Subramanian Syngene International - India


Training

HepatoPearl : a novel easy-to-use 3D micro-liver model for everyday experiments : manipulation, viability staining.

With Noushin Dianat, CYPRIO - France


New tools and models based on different hepatic cells.

With Valery Shevchenko, Biopredic International - France

Direct and quantitative evaluationof the human CYP450 contribution (fm) to drug clearance using a novel
in vitro SILENSOMES™ model.

With Françoise Brée & Ashwani Sharma, Eurosafe - France


Friday, June 23rd 2017

Training

HepaRG™ hep+ and biological tracers for a new in vitro micronucleus assay.

With Gladys Mirey , INRA - France


Novel format of Comet Assay for genotoxicity assessment in metabolically competent HepaRG™ cells.

With Sergey Shaposhnikov, NorGenoTech AS - Norway


HepatoPearl : a novel easy-to-use 3D micro-liver model for everyday experiments : ATP/CYP3A4-Glo assays.

With Noushin Dianat, CYPRIO - France

New patented cholestasis assays based on BAs and paracellular fluorescent probes developed at
Biopredic International .

With Christiane Guillouzo, Marie-Michèle Trancart, Biopredic International and Eurosafe - France

PDF PROGRAM

register caat

 

RESEAU MEETOCHONDRIES - MAY 2017

Logo Meetochondries

Biopredic International is happy to support the next meeting of "Réseau MeetOchondries" who will take place on May 14-17, 2017 in Hossegor (France).

Title: Impact des médicaments contaminants environnementaux sur les fonctions mitochondriales et le métabolisme

Discover the full program

 
  

HepaRG training sessions

Biopredic international offers training sessions to use the Heparg™ cell line and cryopreserved differentiated Heparg™ cells.

  • Session duration: 2 days

  • Training content:

    • Presentation of the HepaRG™ cells

    • HepaRG™ applications

    • HepaRG™ cell culture

    • Hands-on time in Biopredic International's laboratory to experience the handling of the cells and see the key technical steps.

  • Location

The sessions take place in Biopredic International's premises in Saint Gregoire, near Rennes in France. But the training can also be provided as personalised on-site sessions, with on our specialist visiting you.

For more information on the HepaRG™ culture training session and its cost, please contact Biopredic International customer services.

 

Upcoming HepaRG training sessions

SOT - March 2017 - Back to the images

 SOT 2017

BIOPREDIC INTERNATIONAL were present at the 56th SOT meeting two weeks ago. This year’s event was held at the Baltimore, MD convention center with over 6,000 attendees.

Back on 4 days at the SOT 2017 !

Fanny Ben Taarit, Solène Martin and Christophe Chesné on our stand just before the opening of the meeting. 

Biopreic Booth at the SOT

Solenne Martin in front of her poster about the impact of the culture medium composition on the induction of CYP2C8, 2C9, 2C19, and 2D6 by the Assessment of mRNA on Human Hepatocytes

Solenne Martin in front of her poster about the impact of the culture medium composition on the induction of CYP2C8, 2C9, 2C19, and 2D6 by the Assessment of mRNA on Human Hepatocytes

Christiane Guguen-Guillouzo presenting an HepaRG poster: "Development of a Predictive Screening Test for Drugs Liable To Cholestatic Using HepaRG™ Hepatocytes"

Christiane Guguen-Guillouzo presenting an HepaRG poster:  Development of a Predictive Screening Test for Drugs Liable To Cholestatic Using HepaRG Hepatocytes

Christophe Chesné presenting his poster about Anatomical Comparison of Human Female Abdominal Skin with or without Striae Distensae and Effect on Percutaneous Passage and Metabolism Studies

Christophe Chesné presenting his poster about Anatomical Comparison of Human Female Abdominal Skin with or without Striae Distensae and Effect on Percutaneous Passage and Metabolism Studies

Ruoya Li presenting an HepaRG poster: "A Large-Scale Proteomic Map of Differentiated HepaRG™ Cells Highlights Their Pivotal Hepatocyte-Like Metabolic Functions and Interconnecting Specific Regulations"

Ruoya Li presenting an HepaRG poster: A Large-Scale Proteomic Map of Differentiated HepaRG™ Cells Highlights Their Pivotal Hepatocyte-Like Metabolic Functions and Interconnecting Specific Regulations

Joseph Antoun & Christiane Guguen-Guillouzo presenting the infomercial

Joseph Antoun & Christiane Guguen-Guillouzo presenting the infomercial

See you next year for the 57th edition in San Antonio !

More information about HepaRG™ on our website.

SOT - March 2017

 SOT 2017

BIOPREDIC INTERNATIONAL will be present at the 56th SOT meeting on booth 1724.   

Program:

Infomercial:

Tuesday 14th March: 12-1pm - Room 338

Title: A New Pathway and Related Assay Systems and Biomarkers for the Study and Prediction Of Cholestasis Side Effects Xenobiotics

Speaker: Joseph Antoun (Scientific Adviser - Research Instructor of Medicine at Vanderbilt University)

Abstract: Our lecture will rely on two papers published that year and that explain that the bile canaliculi contraction and the RhoK and the MLCk enzymes regulating the level of phosphorylated light chain myosin are the targets of cholestatic compounds.

More information about SOT

Posters:

Ruoya Li, PhD (Project & Product Manager)
Abstract Title:  Development of a Predictive Screening Test for Drugs Liable To Cholestatic Using HepaRG Hepatocytes  Ruoya Li
Session Title: Systems Toxicology
Presentation Date and Time: 3/16/2017 8:30-11:45 AM
Twitter
 
Christiane Guguen-Guillouzo
Abstract Title:  A Large-Scale Proteomic Map of Differentiated HepaRG™ Cells Highlights Their Pivotal Hepatocyte-Like Metabolic Functions and Interconnecting Specific Regulations
Session Title: Biomarkers
Presentation Date and Time: 3/14/2017: 1:15-4:30 PM
Twitter
 
Christophe Chesné, Pharm, PhD (CEO)       
Abstract Title:  Anatomical Comparison of Human Female Abdominal Skin with or without Striae Distensae and Effect on Percutaneous Passage and Metabolism Studies
Session Title: Skin
Presentation Date and Time: 3/14/2017: 1:15-4:30 PM
Linkedin / Twitter


Solenne Martin, PhD (Project Manager & Study Director)
Abstract Title: Impact of the Culture Medium Composition on the Induction of CYP2C8, 2C9, 2C19, and 2D6 by the Assessment of mRNA on Human Hepatocytes
Session Title: Cytochrome P450Presentation
Date and Time: 3/13/2017: 1:15-4:30 PM
Twitter

Presentation Location: CC Exhibit Hall or Hall A (see daily schedule below).

You want to meet us there? 

Visit us on booth 1724 or schedule an appointmoint with a member of our team

SOT
Booth 1724
March 12-16 2017 Baltimore 

SLAS - FEBRUARY 2017

slas 2017

Biopredic International will participate to the SLAS in Washington on February 6-8th.  

Poster presentation :

"Development of a predictive screening test for drugs liable to be cholestatic", Poster number 1060

Tuesday, 7th February - 1-3pm

 

ISBS SFAX - February 2017

isbs

February 16th - 17th 2017

BIOPREDIC INTERNATIONAL is conducting an initiation to cell culture at ISBS SFAX in Tunisia. 

CAAT ACADEMY - 2017

caat academy 2017
 
For the second time, Biopredic International is proudly contributing to the CAAT ACADEMY 2017 program
 
 
BIOPREDIC - HOST:
  • 22nd-23rd June 2017 - We will host a special training session about hepatotoxicity: "Update on the hepatotoxicity AOP landscape and on the ADMET field [SEASON 2]"
Abstract : 
The relevant systems and biomarkers for adressing hepatotoxicity and DDI issues will be the focus for this training. Prediction of hepatotoxicity remains a challenge nowadays. The session will cover those new systems that are commercially available together with their relevance for predicting issues related to Cholestasis, genotoxicity. Participants will be trained on 3 models with various cell systems and Silensomes (fm (fractions metabolized) evaluation).

BIOPREDIC - TRAINER :
Some of our collaborators will participate as trainers in several sessions :
  • September 2017 - Amsterdam : "Hands-on training in quantitative human cell and effect based in vitro bioanalysis for assessing endocrine disrupting compounds (EDCs)" - Valery Shevchenko
  • November 2017 - Vienna : "Kidney toxicity testing & best practices" - Eva-Anne Subileau
 
 

LIVER CONGRESS - JANUARY 2017

Biopredic International will present a poster at the congress Liver Disease and Regeneration in Leuven Belgium on January 12nd at 3pm.

Poster presentation :

Development of a predictive screening test for drugs liable to be cholestatic




We wish you a merry Christmas and a happy new year!

ISSX Workshop - October 2016

TKDG - OCTOBER 2016

ESTIV - OCTOBER 2016

OCTOBER 2016 - ELRIG

OCTOBER 2016 - MDO

Course "Cellular culture : Alternative methods" - Genova, Italy - September 2016

EUROTOX - september 2016

ISSX INDIA - September 2016

ISSX KOREA - JUNE 2016

ELRIG MEETING - 1st prize - MAY 2016

HEPARG WORKSHOP - ITALY - MAY 2016

ELRIG - MAY 2016

SOT - March 2016

Biopredic course "Alternative methods to animal experimentation" - Italy, October 2015

JSSX Tokyo

ISSX Orlando

Elrig Drug Discovery 2015

Hepatocytes available

Eusaat 2015